FUSED MULTICYCLIC COMPOUNDS AND THEIR USE AS PARP1 INHIBITORS

Provided herein are certain fused multicyclic compounds with a multicyclic linker, such as a compound of Formula (I), as PARP1 inhibitors, pharmaceutical compositions comprising the compounds, and method of use of the compounds or pharmaceutical compositions in the treatment of diseases or disorders...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CHEN, Chun-Yen, CHEN, Yan, LI, Ming, GU, Xiang-Ju Justin
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Provided herein are certain fused multicyclic compounds with a multicyclic linker, such as a compound of Formula (I), as PARP1 inhibitors, pharmaceutical compositions comprising the compounds, and method of use of the compounds or pharmaceutical compositions in the treatment of diseases or disorders. L'invention concerne certains composés multicycliques fusionnés dotés d'un lieur multicyclique, tel qu'un composé de formule (I), en tant qu'inhibiteurs de PARP1, des compositions pharmaceutiques comprenant les composés, et un procédé d'utilisation des composés ou des compositions pharmaceutiques dans le traitement de maladies ou de troubles.