PROTONATED PH RESPONSIVE POLYMER ENCAPSULATION OF BISPECIFIC ANTIBODIES AND CYTOKINES

Described herein are therapeutic pH responsive micelle compositions comprising a block copolymer and a biological therapeutic agent useful for the treatment of cancer, methods of making such micelles and intermediate compositions useful for making such micelles. L'invention concerne des composi...

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Hauptverfasser: BHARADWAJ, Gaurav, ALLU, Bhargavi, BURCHAM, Austin, GUTOWSKI, Stephen, SU, Qingtai, HAN, Ruolan, CHEN, Zirong, MILLER, Jason, KALASHNIKOVA, Irina, ZHAO, Tian
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creator BHARADWAJ, Gaurav
ALLU, Bhargavi
BURCHAM, Austin
GUTOWSKI, Stephen
SU, Qingtai
HAN, Ruolan
CHEN, Zirong
MILLER, Jason
KALASHNIKOVA, Irina
ZHAO, Tian
description Described herein are therapeutic pH responsive micelle compositions comprising a block copolymer and a biological therapeutic agent useful for the treatment of cancer, methods of making such micelles and intermediate compositions useful for making such micelles. L'invention concerne des compositions de micelles sensibles au pH thérapeutiques comprenant un copolymère séquencé et un agent thérapeutique biologique utiles pour le traitement du cancer, des procédés de fabrication de telles micelles, ainsi que des compositions intermédiaires utiles pour fabriquer de telles micelles.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PROTONATED PH RESPONSIVE POLYMER ENCAPSULATION OF BISPECIFIC ANTIBODIES AND CYTOKINES
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