PROTONATED PH RESPONSIVE POLYMER ENCAPSULATION OF BISPECIFIC ANTIBODIES AND CYTOKINES

Described herein are therapeutic pH responsive micelle compositions comprising a block copolymer and a biological therapeutic agent useful for the treatment of cancer, methods of making such micelles and intermediate compositions useful for making such micelles. L'invention concerne des composi...

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Hauptverfasser:	BHARADWAJ, Gaurav, ALLU, Bhargavi, BURCHAM, Austin, GUTOWSKI, Stephen, SU, Qingtai, HAN, Ruolan, CHEN, Zirong, MILLER, Jason, KALASHNIKOVA, Irina, ZHAO, Tian
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Described herein are therapeutic pH responsive micelle compositions comprising a block copolymer and a biological therapeutic agent useful for the treatment of cancer, methods of making such micelles and intermediate compositions useful for making such micelles. L'invention concerne des compositions de micelles sensibles au pH thérapeutiques comprenant un copolymère séquencé et un agent thérapeutique biologique utiles pour le traitement du cancer, des procédés de fabrication de telles micelles, ainsi que des compositions intermédiaires utiles pour fabriquer de telles micelles.