RET-LDD PROTEIN DEGRADERS

The present disclosure relates to protein degradation inducing compounds for proto-oncogene tyrosine-protein kinase receptor (RET), which may be either wild type RET or a mutant form of RET useful in the treatment of diseases and disorders mediated by said protein and having the Formula (I). La prés...

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Bibliographische Detailangaben
Hauptverfasser:	PAUL, Anirudra, DHAR, T.G. Murali
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure relates to protein degradation inducing compounds for proto-oncogene tyrosine-protein kinase receptor (RET), which may be either wild type RET or a mutant form of RET useful in the treatment of diseases and disorders mediated by said protein and having the Formula (I). La présente invention concerne des composés induisant la dégradation de protéines pour le récepteur tyrosine-kinase (RET) proto-oncogène, à savoir RET de type sauvage ou une forme mutante de RET, utiles dans le traitement de maladies et de troubles médiés par ladite protéine et ayant la formule (I).