MIXED RELEASE PROFILE POLYMER MICROSPHERE FORMULATIONS COMPRISING OCTREOTIDE AND METHODS FOR MAKING AND USING THE SAME

Mixed release profiled polymer microsphere formulations comprising octreotide are provided. In one aspect, the microsphere formulations are characterized in that octreotide is released in vivo in humans over a period of about 60 days. Methods for making and using the formulations are also provided....

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Bibliographische Detailangaben
Hauptverfasser:	SELLERS, Regan, VILLAROSA, Audrey, CORNELL, Matthew, RICHEY, Tracy, MINROVIC, Bradley
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Mixed release profiled polymer microsphere formulations comprising octreotide are provided. In one aspect, the microsphere formulations are characterized in that octreotide is released in vivo in humans over a period of about 60 days. Methods for making and using the formulations are also provided. L'invention concerne des formulations de microsphères polymères à profil de libération mixte comprenant de l'octréotide. Dans un aspect, les formulations de microsphères sont caractérisées en ce que l'octréotide est libéré in vivo chez des humains sur une période d'environ 60 jours. L'invention porte également sur des procédés de fabrication et d'utilisation de ces formulations.