BIFUNCTIONAL PROTEASES AND USES THEREOF

The compositions and methods described herein are useful for generating and using bifunctional proteases (e.g., targeted sheddases, proteases, or amyloid beta (Aβ)-degrading enzymes)) that cleave polypeptides in a targeted manner. Les compositions et les procédés de l'invention sont utiles pour...

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Bibliographische Detailangaben
Hauptverfasser:	MENDLEIN, John, MUNIZ, Ayse, CASEY, Liam, BAI, Yiqun
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The compositions and methods described herein are useful for generating and using bifunctional proteases (e.g., targeted sheddases, proteases, or amyloid beta (Aβ)-degrading enzymes)) that cleave polypeptides in a targeted manner. Les compositions et les procédés de l'invention sont utiles pour générer et utiliser des protéases bifonctionnelles (par exemple, des sheddases, des protéases ou des enzymes de dégradation de bêta-amyloïde (Aβ) ciblées) qui clivent des polypeptides d'une manière ciblée.