IMMUNOGENIC COMPOSITIONS AGAINST INFLUENZA AND RSV

The present disclosure relates to compositions comprising RNA molecules encoding an antigen derived from influenza, wherein the RNA is formulated in a lipid nanoparticle (LNP), and wherein the composition further includes a polypeptide antigen derived from respiratory syncytial virus (RSV). The comp...

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Hauptverfasser:	DIAZ, Fernando Martin, VAN DEYCK, Vincent Jurgen L, ALLEN, Pirada Suphaphiphat, MENG, Fanyu, BHATNAGAR, Bakul Subodh, WEISER, Sarah Elizabeth, PHELAN, Lynn Marie, RAMESAR, Naomi Sasha, BADKAR, Advait Vijay, CHEN, Wei, KOLHE, Parag, VAN MEERVENNE, Bert George E, BRUCHSALER, Michael David, KNAPEN, Wouter Joris, NAUTA, Marjoh Anne, VANSLEMBROUCK, Thijs, SONJE, Jayesh Vijay, LUKSHA, Nicholas, TCHESSALOV, Serguei, SWANSON, Kena Anne, DARVARI, Ramin
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates to compositions comprising RNA molecules encoding an antigen derived from influenza, wherein the RNA is formulated in a lipid nanoparticle (LNP), and wherein the composition further includes a polypeptide antigen derived from respiratory syncytial virus (RSV). The composition may be used for the prevention of illnesses induced by influenza and RSV infection. La présente invention concerne des compositions comprenant des molécules d'ARN codant pour un antigène dérivé de la grippe, l'ARN étant formulé dans une nanoparticule lipidique (LNP), et la composition comprenant en outre un antigène polypeptidique dérivé du virus respiratoire syncytial (VRS). La composition peut être utilisée pour la prévention de maladies induites par la grippe et l'infection par le VRS.