CELL WALL SYNTHESIS-RELATED PROTEIN UGMA, GENE ENCODING SAME, AND USE THEREOF

The present invention relates to the field of biotechnology, and provides a cell wall synthesis-related protein UGMA, a gene encoding same, and a use thereof. The use of the cell wall synthesis-related protein UGMA or the gene encoding the protein comprises any one of: a use in reducing the virulenc...

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Bibliographische Detailangaben
Hauptverfasser:	DENG, Yuanyu, CHEN, Huaigu, SHU, Yan, CAO, Shulin, LI, Wei, SUN, Haiyan
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW PLANTS OR PROCESSES FOR OBTAINING THEM PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the field of biotechnology, and provides a cell wall synthesis-related protein UGMA, a gene encoding same, and a use thereof. The use of the cell wall synthesis-related protein UGMA or the gene encoding the protein comprises any one of: a use in reducing the virulence of a plant fungal pathogen; a use in inhibiting the growth and development of a plant fungal pathogen; a use in screening and/or preparation of a UGMA protein inhibitor; and a use in screening and/or preparation of a chemical for a plant fungal disease, wherein the amino acid sequence of UGMA is shown in SEQ ID NO: 1; the nucleotide sequence of the gene is shown in SEQ ID NO: 2. By knocking out a ugmA gene in pathogenic bacteria, a ugmA gene deletion mutant is obtained, and it is found that the growth and virulence thereof are severely inhibited, and the cell wall thereof is abnormally thickened. Targeted compounds are also obtained by means of virtual screening, thereby providing a new way for research and devel