MONOAMINE OXIDASE (MAO) ELECTROCHEMICAL BIOSENSOR AND USES THEREOF

Described herein is an amperometric biosensor, e.g., chronoamperometric biosensor for the measurement of the concentration of amine-comprising substates, including dopamine, octopamine, tyramine, norepinephrine, tryptamine, 5-methoxytryptamine, and/or hexylamine. The biosensor disclosed herein compr...

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Bibliographische Detailangaben
Hauptverfasser:	TARARINA, Margarita Alexandrovna, ALLEN, Karen, KUZMANOVIC, Uros, GALAGAN, James, MUELLERS, Samantha
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES DIAGNOSIS ENZYMOLOGY HUMAN NECESSITIES HYGIENE IDENTIFICATION INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS SURGERY TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described herein is an amperometric biosensor, e.g., chronoamperometric biosensor for the measurement of the concentration of amine-comprising substates, including dopamine, octopamine, tyramine, norepinephrine, tryptamine, 5-methoxytryptamine, and/or hexylamine. The biosensor disclosed herein comprises a monoamine oxidase (MAO) enzyme, such as Corynebacterium ammoniagenes MAO (caMAO). Also described herein are systems comprising said amperometric biosensor, e.g., chronoamperometric biosensor and methods of using said biosensors. Est décrit un biocapteur ampérométrique, par exemple, un biocapteur chronoampérométrique pour la mesure de la concentration de substrats comprenant une amine, comprenant la dopamine, l'octopamine, la tyramine, la norépinéphrine, la tryptamine, la 5-méthoxytryptamine et/ou l'hexylamine. Le biocapteur divulgué comprend une enzyme monoamine oxydase (MAO), telle que Corynebacterium ammoniagenes MAO (caMAO). Sont également décrits des systèmes comprenant ledit biocapteur ampérométrique, par exemple, un biocapteur chronoampérométrique et des procédés d'utilisation desdits biocapteurs.