ENGINEERED TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE VARIANTS

The present invention provides engineered terminal deoxynucleotidyl transferase (TdT) polypeptides useful in template-independent polynucleotide synthesis, as well as compositions, methods of utilizing these engineered polypeptides, and polynucleotides encoding the engineered terminal deoxynucleotid...

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Bibliographische Detailangaben
Hauptverfasser:	FORGET, Stephanie, ENTWISTLE, David, VOJCIC, Ljubica, MAHMOODI, Niusha, LI, Michelle, WATTS, David, REEVES, Ryan, WONG, Leland, VROOM, Jonathan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides engineered terminal deoxynucleotidyl transferase (TdT) polypeptides useful in template-independent polynucleotide synthesis, as well as compositions, methods of utilizing these engineered polypeptides, and polynucleotides encoding the engineered terminal deoxynucleotidyl transferases. La présente invention concerne des polypeptides de désoxynucléotidyl transférase terminale (TdT) modifiés utiles dans la synthèse de polynucléotides indépendante du modèle, ainsi que des compositions, des procédés d'utilisation de ces polypeptides modifiés, et des polynucléotides codant pour les désoxynucléotidyl transférases terminales modifiées.