INDAZOLE PYRIDONE COMPOUNDS AND USES THEREOF

Novel tetracyclic pyridone compounds according to Formula I are provided, (I) where R and X are defined herein. Pharmaceutical compositions containing such compounds, methods of using these compounds and compositions in the treatment and prevention of HBV infections are also provided. L'inventi...

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Bibliographische Detailangaben
Hauptverfasser:	SHULMAN, Nancy, KOLTUN, Dmitry, JAVANBAKHT, Hassan, CHU, Keting, ZABLOCKI, Jeffery
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Novel tetracyclic pyridone compounds according to Formula I are provided, (I) where R and X are defined herein. Pharmaceutical compositions containing such compounds, methods of using these compounds and compositions in the treatment and prevention of HBV infections are also provided. L'invention concerne de nouveaux composés de pyridone tétracycliques selon la formule I, (I) R et X étant tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques contenant de tels composés, des méthodes d'utilisation desdits composés et compositions dans le traitement et la prévention d'infections par le VHB.