HSD17B13 INHIBITORS AND/OR DEGRADERS

Described herein are compounds of Formula I, wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH. L'invention concerne des composés de formule I, le...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	ZHANG, Liying, LEE, Jisun, DUTRA, Jason Kenneth, ZHANG, Lei, WRIGHT, Ann Sorrentino, HOU, Xinjun, ADAMS, Jan Antoinette Cusi Romero, GARNSEY, Michelle Renee, NASON II, Deane Milford, WANG, Yang, EDMONDS, David James, O, NEILL, RANKIC, Danica Antonia, BECHLE, Bruce Michael
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Described herein are compounds of Formula I, wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH. L'invention concerne des composés de formule I, les variables étant définies dans la description, leur utilisation en tant qu'inhibiteurs et/ou agents de dégradation de HSD17B13, des compositions pharmaceutiques contenant de tels composés et leur utilisation pour traiter, par exemple, la NAFLD et la NASH.