HUMANIZED ANTIBODIES AGAINST NECTIN-4 AND DRUG CONJUGATES THEREOF

The present invention provides humanized antibodies against Nectin-4 and antibody drug conjugates (ADCs) of the humanized antibodies and use thereof in treating diseases, in particular cancer. La présente invention concerne des anticorps humanisés dirigés contre la nectine-4 et des conjugués anticor...

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Bibliographische Detailangaben
Hauptverfasser:	VITENSHTEIN, Alon, CINAMON, Guy, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides humanized antibodies against Nectin-4 and antibody drug conjugates (ADCs) of the humanized antibodies and use thereof in treating diseases, in particular cancer. La présente invention concerne des anticorps humanisés dirigés contre la nectine-4 et des conjugués anticorps-médicament (ADC) des anticorps humanisés, ainsi qu'une utilisation associée dans le traitement de maladies, en particulier de cancer.