AAV VECTORS ENCODING OXIDOREDUCTASE ENZYME AND USES THEREOF

Provided are recombinant adeno-associated virus (rAAV) vectors, methods of treating an ocular condition, pharmaceutical compositions, and other compositions and methods, in which the rAAV vector comprises a polynucleotide encoding oxidoreductase enzymes. Methods of treatment may include administrati...

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Bibliographische Detailangaben
Hauptverfasser:	NAU, Jeffrey Alan, CARLSON, Eric C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided are recombinant adeno-associated virus (rAAV) vectors, methods of treating an ocular condition, pharmaceutical compositions, and other compositions and methods, in which the rAAV vector comprises a polynucleotide encoding oxidoreductase enzymes. Methods of treatment may include administration to the lacrimal gland. L'invention concerne des vecteurs de virus adéno-associé recombinant (rAAV), des méthodes de traitement d'une affection oculaire, des compositions pharmaceutiques et d'autres compositions et méthodes, le vecteur rAAV comprenant un polynucléotide codant pour des enzymes oxydoréductase. Des méthodes de traitement peuvent comprendre une administration à la glande lacrymale.