PEPTIDE THERAPEUTICS AGAINST SARS-COV-2 SPIKE PROTEIN

Proteinaceous therapeutics, such as antibodies and fusion proteins, for preventing, reducing the occurrence of, and/or treating a SARS-CoV-2 infection in a subject are provided herein. The methods provided herein include administering to a subject an antigen binding fragments (Fab fragment) or antib...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NELSON, Jay Gardner, BUZKO, Oleksandr, HIGASHIDE, Wendy M, OLSON, Clifford Anders, NIAZI, Kayvan, SOON-SHIONG, Patrick, TANAKA, Shiho
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Proteinaceous therapeutics, such as antibodies and fusion proteins, for preventing, reducing the occurrence of, and/or treating a SARS-CoV-2 infection in a subject are provided herein. The methods provided herein include administering to a subject an antigen binding fragments (Fab fragment) or antibody that binds to the SARS-CoV-2 Spike protein, and/or a DNA construct encoding an anti-Spike Fab fragment. L'invention concerne des agents thérapeutiques protéiques, tels que des anticorps et des protéines de fusion, pour la prévention, la réduction de l'apparition et/ou le traitement d'une infection à SARS-CoV-2 chez un sujet. Les méthodes de l'invention comprennent l'administration à un sujet d'un fragment de liaison à l'antigène (fragment Fab) ou d'un anticorps qui se lie à la protéine de spicule du SARS-CoV-2, et/ou d'une construction d'ADN codant pour un fragment Fab anti-spicule.