PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED
Disclosed herein are small molecule modulators of pannexin. Also disclosed herein are methods of treating disorders associated with exacerbated activation of ATP- induced signal pathways mediated by pannexin, such as pain and opioid addiction, by administering small molecule modulators of pannexin....
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| Format: | Patent |
| Sprache: | eng ; fre |
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| Zusammenfassung: | Disclosed herein are small molecule modulators of pannexin. Also disclosed herein are methods of treating disorders associated with exacerbated activation of ATP- induced signal pathways mediated by pannexin, such as pain and opioid addiction, by administering small molecule modulators of pannexin.
L'invention concerne des modulateurs à petites molécules de la pannexine. L'invention concerne également des méthodes de traitement de troubles associés à l'activation exacerbée de voies de signal induites par l'ATP médiées par la pannexine, telles que la douleur et la dépendance aux opioïdes, par l'administration de modulateurs à petites molécules de la pannexine. |
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