NOVEL COCRYSTALS OF METHYLXANTHINES, THEIR POLYMORPHS AND PROCESS THEREOF

The present invention relates to cocrystals of Methylxanthines with Stilbenoids as coformers, their polymorphic forms and to the process for preparation thereof. The debittering of Methylxanthines is carried out by co-crystallization using Stilbenoids as coformers. The invention further relates to t...

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Hauptverfasser:	KANUMURU, Rahul Raju, KOCHUMALAYIL, Shaji George, VANA, Murali Mohanarao, SURANENI, Ravikumar
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to cocrystals of Methylxanthines with Stilbenoids as coformers, their polymorphic forms and to the process for preparation thereof. The debittering of Methylxanthines is carried out by co-crystallization using Stilbenoids as coformers. The invention further relates to the preparation of polymorphic forms of debittered cocrystals and their use in nutraceutical and pharmaceutical compositions. La présente invention concerne des co-cristaux de méthylxanthines avec des stilbénoïdes en tant que co-formeurs, leurs formes polymorphes et leur procédé de préparation. La désamérisation de méthylxanthines est réalisée par co-cristallisation à l'aide de stilbénoïdes en tant que co-formeurs. L'invention concerne en outre la préparation de formes polymorphes de co-cristaux désamérisés et leur utilisation dans des compositions nutraceutiques et pharmaceutiques.