THERAPEUTIC USE OF THE miR155 SNP rs377265631

The present invention relates to the therapeutic use of a single nucleotide polymorphism (SNP) of miR155. The SNP has a multifunctional beneficial effect on immune cells, such as T cells and can be recombinantly employed in the treatment of diseases, such as cancer. La présente invention concerne l&...

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Hauptverfasser: GATTINONI, Luca, LACEY, Neal, JI, Yun, SLAVKOVIC-LUKIC, Dragana
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to the therapeutic use of a single nucleotide polymorphism (SNP) of miR155. The SNP has a multifunctional beneficial effect on immune cells, such as T cells and can be recombinantly employed in the treatment of diseases, such as cancer. La présente invention concerne l'utilisation thérapeutique d'un polymorphisme mononucléotidique (SNP) de miR155. Le SNP présente un effet bénéfique multifonctionnel sur les lymphocytes, tels que les lymphocytes T, et peut être utilisé de manière recombinée dans le traitement de maladies, telles que le cancer.