CELLULAR MATRIX NERVE GRAFT FOR REPAIRING PERIPHERAL NERVE INJURY AND PREPARATION METHOD THEREFOR

Disclosed are a cellular matrix nerve graft for repairing peripheral nerve injury and a preparation method therefor. The cellular matrix nerve graft comprises an acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization of the matrix secreted by stem cells, and t...

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Hauptverfasser: XU, Lingchi, WANG, Shanshan, QIAN, Tianmei, XU, Lai, LI, Meiyuan, GONG, Leilei, GU, Xiaosong, SUN, Hualin, WANG, Hongkui
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creator XU, Lingchi
WANG, Shanshan
QIAN, Tianmei
XU, Lai
LI, Meiyuan
GONG, Leilei
GU, Xiaosong
SUN, Hualin
WANG, Hongkui
description Disclosed are a cellular matrix nerve graft for repairing peripheral nerve injury and a preparation method therefor. The cellular matrix nerve graft comprises an acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization of the matrix secreted by stem cells, and the acellular matrix is wrapped around the scaffold. With the graft, the defects of autologous nerve transplantation repair can be overcome, and the immunogenicity of allogeneic cell transplantation repair is avoided. The present invention provides a cellular matrix nerve graft conducive to nerve cell proliferation and migration, which can establish a microenvironment conducive to axon growth, thereby achieving the purposes of nerve regeneration and function repair. The present invention provides a feasible solution for clinical treatment of nerve defects. L'invention concerne un greffon nerveux à matrice cellulaire pour réparer une lésion du nerf périphérique et son procédé de préparation. Le greffon nerveux à matr
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The cellular matrix nerve graft comprises an acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization of the matrix secreted by stem cells, and the acellular matrix is wrapped around the scaffold. With the graft, the defects of autologous nerve transplantation repair can be overcome, and the immunogenicity of allogeneic cell transplantation repair is avoided. The present invention provides a cellular matrix nerve graft conducive to nerve cell proliferation and migration, which can establish a microenvironment conducive to axon growth, thereby achieving the purposes of nerve regeneration and function repair. The present invention provides a feasible solution for clinical treatment of nerve defects. L'invention concerne un greffon nerveux à matrice cellulaire pour réparer une lésion du nerf périphérique et son procédé de préparation. 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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
title CELLULAR MATRIX NERVE GRAFT FOR REPAIRING PERIPHERAL NERVE INJURY AND PREPARATION METHOD THEREFOR
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