COMPOSITIONS AND METHODS FOR ADENO-ASSOCIATED VIRAL PRODUCTION

Disclosed herein are cell genetically engineered cells for AAV production. The genetically engineered cells comprise molecular systems for temporal control of expression of genes required for AAV production. Also disclosed herein are methods of using genetically engineered cells for AAV production....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MCMAHAN, Jeffrey, GAM, Jeremy, NIELSEN, Alec
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed herein are cell genetically engineered cells for AAV production. The genetically engineered cells comprise molecular systems for temporal control of expression of genes required for AAV production. Also disclosed herein are methods of using genetically engineered cells for AAV production. Further, wherein the expression control component comprises a polynucleic acid molecule encoding for a recombinase. L'invention concerne des cellules génétiquement modifiées pour la production de virus adéno-associé (AAV). Les cellules génétiquement modifiées comprennent des systèmes moléculaires pour la régulation temporelle de l'expression de gènes requis pour la production d'AAV. L'invention concerne également des procédés d'utilisation de cellules génétiquement modifiées pour la production d'AAV.