SUSTAINED-RELEASE ORAL FOSAMPRENAVIR FORMULATION FOR TREATMENT OF REFLUX

SUSTAINED-RELEASE ORAL FOSAMPRENAVIR FORMULATION FOR TREATMENT OF REFLUX

The present invention provides methods of treating airway reflux using an HIV protease inhibitor that is capable of binding to and inhibiting the enzymatic activity of pepsin. Compositions comprising sustained release formulations of HIV protease inhibitors are also provided for oral administration....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JOHNSTON, Nikki, VIGILE, Franco Gennaro
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention provides methods of treating airway reflux using an HIV protease inhibitor that is capable of binding to and inhibiting the enzymatic activity of pepsin. Compositions comprising sustained release formulations of HIV protease inhibitors are also provided for oral administration. La présente invention concerne des méthodes de traitement du reflux des voies respiratoires à l'aide d'un inhibiteur de la protéase du VIH qui est capable de se lier à la pepsine et d'inhiber son activité enzymatique. L'invention concerne également des compositions comprenant des formulations à libération prolongée d'inhibiteurs de la protéase du VIH pour une administration orale.