OSMOTIC PUMP CONTROLLED RELEASE PREPARATION, OSMOTIC PUMP CONTROLLED RELEASE COMPOSITION, PREPARATION METHOD AND USE

An osmotic pump controlled release preparation, which comprises the following structures sequentially arranged from inside out: a tablet core containing a drug-containing layer and a push layer, a controlled-release coating layer having a drug release hole, and an optional water-soluble coating film...

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Bibliographische Detailangaben
Hauptverfasser: ZHU, Quanlei, YAN, Hu, YOU, Heng, ZHU, Chunliu, GAN, Yong, WANG, Suyun, HU, Jie
Format: Patent
Sprache:chi ; eng ; fre
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Beschreibung
Zusammenfassung:An osmotic pump controlled release preparation, which comprises the following structures sequentially arranged from inside out: a tablet core containing a drug-containing layer and a push layer, a controlled-release coating layer having a drug release hole, and an optional water-soluble coating film; wherein the drug release hole establishes communication between the drug-containing layer and the outside of the osmotic pump controlled-release preparation; the push layer is located at the side of the drug-containing layer away from the drug release hole; the drug-containing layer comprises an active pharmaceutical ingredient, the push layer comprises an osmopolymer, and the osmopolymer comprises hydroxyethyl cellulose and alginate. Une préparation à libération contrôlée par pompe osmotique, qui comprend les structures suivantes disposées séquentiellement de l'intérieur à l'extérieur : un noyau de comprimé contenant une couche contenant un médicament et une couche de poussée, une couche de revêtement à libérati