METHODS FOR PURIFYING RECOMBINANT POLYPEPTIDES

The present invention is directed to a novel process for purifying a recombinant polypeptide from a solution containing one or more impurities. The process may include a chromatography process which includes a wash buffer containing a small ionic radius cation and a large ionic radius anion. La prés...

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Bibliographische Detailangaben
Hauptverfasser: TERFLOTH, Gerald J, LEVY, Nicholas E
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention is directed to a novel process for purifying a recombinant polypeptide from a solution containing one or more impurities. The process may include a chromatography process which includes a wash buffer containing a small ionic radius cation and a large ionic radius anion. La présente invention concerne un nouveau procédé de purification d'un polypeptide recombinant à partir d'une solution contenant une ou plusieurs impuretés. Le procédé peut comprendre un processus de chromatographie qui comprend un tampon de lavage contenant un cation à faible rayon ionique et un anion à rayon ionique élevé.