EXTRACELLULAR VESICLE COMPRISING ANTIGENIC PROTEIN OR GENE ENCODING SAME PROTEIN, AND USES THEREOF

The present invention relates to an extracellular vesicle comprising an antigenic protein or a gene encoding the antigenic protein and uses thereof and, more specifically, to an extracellular vesicle comprising an antigenic protein derived from viruses, microorganisms, or cancer cells, or to a gene...

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Bibliographische Detailangaben
Hauptverfasser:	KWON, Ki Hwan, KIM, Kyoung Hwa, CHUNG, Ji Hwa
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to an extracellular vesicle comprising an antigenic protein or a gene encoding the antigenic protein and uses thereof and, more specifically, to an extracellular vesicle comprising an antigenic protein derived from viruses, microorganisms, or cancer cells, or to a gene encoding the antigenic protein, or to a vaccine composition for the prevention or treatment of viral infections, microbial infections, or cancer comprising same. The extracellular vesicle, or the vaccine composition comprising same, according to the present invention, is expected to be useful in the development of vaccines for the prevention or treatment of various diseases, including viral infections, microbial infections, or cancer, as a platform applicable to various diseases with excellent antigen-specific immune response inducing effects and stability. La présente invention concerne une vésicule extracellulaire comprenant une protéine antigénique ou un gène codant pour la protéine antigénique et ses utilisations et, plus particulièrement, une vésicule extracellulaire comprenant une protéine antigénique issue de virus, de micro-organismes ou de cellules cancéreuses, ou un gène codant pour la protéine antigénique, ou une composition vaccinale pour la prévention ou le traitement d'infections virales, d'infections microbiennes ou de cancers la comprenant. La vésicule extracellulaire, ou la composition de vaccin le comprenant, selon la présente invention, est censée être utile dans le développement de vaccins pour la prévention ou le traitement de diverses maladies, y compris des infections virales, des infections microbiennes ou le cancer, en tant que plateforme applicable à diverses maladies ayant d'excellentes effets induisant une réponse immunitaire spécifique à un antigène et une excellente stabilité. 본 발명은 항원 단백질 또는 상기 단백질을 암호화하는 유전자를 포함하는 세포외소포체 및 그의 용도에 관한 것으로서, 보다 구체적으로는 바이러스, 미생물 또는 암세포 유래 항원 단백질 또는 상기 단백질을 암호화하는 유전자를 포함하는 세포외소포체 또는 이를 포함하는 바이러스 감염증, 미생물 감염증 또는 암의 예방 또는 치료용 백신 조성물에 관한 것이다. 본 발명에 따른 세포외소포체 또는 이를 포함하는 백신 조성물은 우수한 항원 특이적 면역반응 유도 효과 및 안정성을 갖춘 다양한 질환에 적용 가능한 플랫폼으로써 바이러스 감염증, 미생물 감염증 또는 암을 포함한 다양한 질환의 예방 또는 치료용 백신 개발분야에서 유용하게 활용될 수 있을 것으로 기대된다.