IMPROVED ASSAY COMPOSITIONS AND METHODS

This disclosure provides improved assays and assay methods that include compositions comprising enzymes, such as ALP, conjugated to an antigen or antibody, as well as compositions that include enzyme substrates, wherein the compositions are optimized and adapted to provide improved assay performance...

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Bibliographische Detailangaben
Hauptverfasser: WOLFE, Lauren, KNUTSON, Christopher R, HOLLAND, Mark D, SZABO, Milos, KJOME, Michael T, CARLSON, Corey M
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:This disclosure provides improved assays and assay methods that include compositions comprising enzymes, such as ALP, conjugated to an antigen or antibody, as well as compositions that include enzyme substrates, wherein the compositions are optimized and adapted to provide improved assay performance. The disclosure also describes compositions of matter and kits that comprise the compositions for use in immunoassays. La présente divulgation concerne des dosages et des procédés de dosage améliorés qui comprennent des compositions comprenant des enzymes, telles que l'ALP, conjuguées à un antigène ou à un anticorps, ainsi que des compositions qui comprennent des substrats enzymatiques, les compositions étant optimisées et conçues pour assurer des performances de dosage améliorées. La divulgation concerne également des compositions de substances et des kits qui comprennent les compositions destinées à être utilisées dans des dosages immunologiques.