ENGINEERED HUMAN SERINE DEHYDRATASE ENZYMES AND METHODS FOR TREATING CANCER
Disclosed herein are compositions related to polypeptides with serine and/or threonine-degrading enzyme activity. Also disclosed are nucleic acids, expression vectors, host cells, and pharmaceutical formulations related to the polypeptides. Further disclosed are methods of using the pharmaceutical f...
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| creator | CAYIR, Ebru DIAZ, Daniel STONE, Everett SHROFF, Raghav |
| description | Disclosed herein are compositions related to polypeptides with serine and/or threonine-degrading enzyme activity. Also disclosed are nucleic acids, expression vectors, host cells, and pharmaceutical formulations related to the polypeptides. Further disclosed are methods of using the pharmaceutical formulations comprising above to treat cancer.
L'invention concerne des compositions associées à des polypeptides ayant une activité enzymatique de dégradation de sérine et/ou de thréonine. L'invention concerne également des acides nucléiques, des vecteurs d'expression, des cellules hôtes et des formulations pharmaceutiques associées aux polypeptides. L'invention concerne en outre des procédés d'utilisation des formulations pharmaceutiques susmentionnées pour traiter le cancer. |
| format | Patent |
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L'invention concerne des compositions associées à des polypeptides ayant une activité enzymatique de dégradation de sérine et/ou de thréonine. L'invention concerne également des acides nucléiques, des vecteurs d'expression, des cellules hôtes et des formulations pharmaceutiques associées aux polypeptides. L'invention concerne en outre des procédés d'utilisation des formulations pharmaceutiques susmentionnées pour traiter le cancer.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240104&DB=EPODOC&CC=WO&NR=2024006973A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240104&DB=EPODOC&CC=WO&NR=2024006973A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAYIR, Ebru</creatorcontrib><creatorcontrib>DIAZ, Daniel</creatorcontrib><creatorcontrib>STONE, Everett</creatorcontrib><creatorcontrib>SHROFF, Raghav</creatorcontrib><title>ENGINEERED HUMAN SERINE DEHYDRATASE ENZYMES AND METHODS FOR TREATING CANCER</title><description>Disclosed herein are compositions related to polypeptides with serine and/or threonine-degrading enzyme activity. Also disclosed are nucleic acids, expression vectors, host cells, and pharmaceutical formulations related to the polypeptides. Further disclosed are methods of using the pharmaceutical formulations comprising above to treat cancer.
L'invention concerne des compositions associées à des polypeptides ayant une activité enzymatique de dégradation de sérine et/ou de thréonine. L'invention concerne également des acides nucléiques, des vecteurs d'expression, des cellules hôtes et des formulations pharmaceutiques associées aux polypeptides. L'invention concerne en outre des procédés d'utilisation des formulations pharmaceutiques susmentionnées pour traiter le cancer.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAURuEuDqK-wwVnIbaiOF6Sv02R3EASkbqUInESLdT3RwcfwOnAx5kXJ0jTChBgyJ4dC0WEL5CB7UzgxBEEuXYOkVgMOSTrTaTaB0oBnFppSLNohGUxuw-PKa9-XRTrGknbTR5ffZ7G4Zaf-d1ffKnKnVL746HibfXf9QE-ZS6K</recordid><startdate>20240104</startdate><enddate>20240104</enddate><creator>CAYIR, Ebru</creator><creator>DIAZ, Daniel</creator><creator>STONE, Everett</creator><creator>SHROFF, Raghav</creator><scope>EVB</scope></search><sort><creationdate>20240104</creationdate><title>ENGINEERED HUMAN SERINE DEHYDRATASE ENZYMES AND METHODS FOR TREATING CANCER</title><author>CAYIR, Ebru ; DIAZ, Daniel ; STONE, Everett ; SHROFF, Raghav</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024006973A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>CAYIR, Ebru</creatorcontrib><creatorcontrib>DIAZ, Daniel</creatorcontrib><creatorcontrib>STONE, Everett</creatorcontrib><creatorcontrib>SHROFF, Raghav</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CAYIR, Ebru</au><au>DIAZ, Daniel</au><au>STONE, Everett</au><au>SHROFF, Raghav</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ENGINEERED HUMAN SERINE DEHYDRATASE ENZYMES AND METHODS FOR TREATING CANCER</title><date>2024-01-04</date><risdate>2024</risdate><abstract>Disclosed herein are compositions related to polypeptides with serine and/or threonine-degrading enzyme activity. Also disclosed are nucleic acids, expression vectors, host cells, and pharmaceutical formulations related to the polypeptides. Further disclosed are methods of using the pharmaceutical formulations comprising above to treat cancer.
L'invention concerne des compositions associées à des polypeptides ayant une activité enzymatique de dégradation de sérine et/ou de thréonine. L'invention concerne également des acides nucléiques, des vecteurs d'expression, des cellules hôtes et des formulations pharmaceutiques associées aux polypeptides. L'invention concerne en outre des procédés d'utilisation des formulations pharmaceutiques susmentionnées pour traiter le cancer.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | ENGINEERED HUMAN SERINE DEHYDRATASE ENZYMES AND METHODS FOR TREATING CANCER |
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