ENGINEERED HUMAN SERINE DEHYDRATASE ENZYMES AND METHODS FOR TREATING CANCER

Disclosed herein are compositions related to polypeptides with serine and/or threonine-degrading enzyme activity. Also disclosed are nucleic acids, expression vectors, host cells, and pharmaceutical formulations related to the polypeptides. Further disclosed are methods of using the pharmaceutical f...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CAYIR, Ebru, DIAZ, Daniel, STONE, Everett, SHROFF, Raghav
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed herein are compositions related to polypeptides with serine and/or threonine-degrading enzyme activity. Also disclosed are nucleic acids, expression vectors, host cells, and pharmaceutical formulations related to the polypeptides. Further disclosed are methods of using the pharmaceutical formulations comprising above to treat cancer. L'invention concerne des compositions associées à des polypeptides ayant une activité enzymatique de dégradation de sérine et/ou de thréonine. L'invention concerne également des acides nucléiques, des vecteurs d'expression, des cellules hôtes et des formulations pharmaceutiques associées aux polypeptides. L'invention concerne en outre des procédés d'utilisation des formulations pharmaceutiques susmentionnées pour traiter le cancer.