STORAGE STABLE TOPICAL COMPOSITION COMPRISING CLOBETASOL

The present invention provides a storage stable clobetasol topical formulation comprising cetostearyl alcohol and glyceryl stearate in a specific weight percent based on the total composition and comprising citric acid as a pH modifier. The amount of citric acid in the formulation is at least 0.05%...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	PINARBASLI, Onur, SARRACOGLU, Nagehan, AYBEY DOGANAY, Asuman, KOKSEL OZGEN, Bahar, ONCEL, Hatice, ATILGAN, Nurdan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention provides a storage stable clobetasol topical formulation comprising cetostearyl alcohol and glyceryl stearate in a specific weight percent based on the total composition and comprising citric acid as a pH modifier. The amount of citric acid in the formulation is at least 0.05% (w/w) and the product has a pH of 5 to 7 throughout the stability condition. La présente invention concerne une formulation topique de clobétasol stable au stockage comprenant de l'alcool cétostéaryle et du stéarate de glycéryle dans un pourcentage en poids spécifique sur la base de la composition totale et comprenant de l'acide citrique en tant que modificateur de pH. La quantité d'acide citrique dans la formulation est d'au moins 0,05 % (p/p) et le produit a un pH de 5 à 7 à l'état stable.