1,4-DIPHENYL-1 H-INDAZOLE AND 1-PYRIDIN-2-YL-4-PHENYL-1 H-INDAZOLE DERIVATIVES AS PD-1/PD-L1 MODULATORS FOR THE TREATMENT OF CANCER

The present disclosure relates to compounds of Formula (I): The compounds disclosed herein are useful for modulating PD-1 activity, PD-L1 activity (programmed cell death protein 1), and/or the PD-1/PD-L1 interaction and may be used in the treatment of disorders in which PD-1 activity, PD-L1 activity...

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Hauptverfasser:	THAVORNSIN, Nopparat, DEESIRI, Sirikan, CHAROENPAKDEE, Chayan, PISITKUN, Trairak, RATTANANGKOOL, Eakkaphon, AMPAWA, Supanan, SRISA, Jakkrit, DUNKOKSUNG, Wilasinee, BURANAPRADITKUN, Supranee, JIRAPONGWATTANA, Niphat, HIRANKARN, Nattiya, UDOMNILOBOL, Udomsak, NALINRATANA, Nonthaneth, PRUEKSARITANONT, Thomayant, RUENGSATRA, Tanachote, SOPONPONG, Jakapun, SONGTHAMMANUPHAP, Songkiat
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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