TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS
The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor. La présente invention concerne des comp...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LAWSON, John David KULYK, Svitlana SMITH, Christopher Ronald MARX, Matthew Arnold IVETAC, Anthony WANG, Xiaolun |
| description | The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
La présente invention concerne des composés qui inhibent au moins une mutation parmi KRas de type sauvage, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D et KRas Q61H, des compositions pharmaceutiques comprenant ces composés et leurs méthodes d'utilisation. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2023244604A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2023244604A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2023244604A13</originalsourceid><addsrcrecordid>eNrjZNALcQ0JcvSIdAnyD4gM8nQBk76eLp5-rgoBjn663kGOwQqefh6eTp4h_kHBPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7UkPtzfyMDI2MjExMzAxNHQmDhVAMvCJ0o</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS</title><source>esp@cenet</source><creator>LAWSON, John David ; KULYK, Svitlana ; SMITH, Christopher Ronald ; MARX, Matthew Arnold ; IVETAC, Anthony ; WANG, Xiaolun</creator><creatorcontrib>LAWSON, John David ; KULYK, Svitlana ; SMITH, Christopher Ronald ; MARX, Matthew Arnold ; IVETAC, Anthony ; WANG, Xiaolun</creatorcontrib><description>The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
La présente invention concerne des composés qui inhibent au moins une mutation parmi KRas de type sauvage, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D et KRas Q61H, des compositions pharmaceutiques comprenant ces composés et leurs méthodes d'utilisation.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231221&DB=EPODOC&CC=WO&NR=2023244604A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231221&DB=EPODOC&CC=WO&NR=2023244604A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LAWSON, John David</creatorcontrib><creatorcontrib>KULYK, Svitlana</creatorcontrib><creatorcontrib>SMITH, Christopher Ronald</creatorcontrib><creatorcontrib>MARX, Matthew Arnold</creatorcontrib><creatorcontrib>IVETAC, Anthony</creatorcontrib><creatorcontrib>WANG, Xiaolun</creatorcontrib><title>TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS</title><description>The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
La présente invention concerne des composés qui inhibent au moins une mutation parmi KRas de type sauvage, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D et KRas Q61H, des compositions pharmaceutiques comprenant ces composés et leurs méthodes d'utilisation.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNALcQ0JcvSIdAnyD4gM8nQBk76eLp5-rgoBjn663kGOwQqefh6eTp4h_kHBPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7UkPtzfyMDI2MjExMzAxNHQmDhVAMvCJ0o</recordid><startdate>20231221</startdate><enddate>20231221</enddate><creator>LAWSON, John David</creator><creator>KULYK, Svitlana</creator><creator>SMITH, Christopher Ronald</creator><creator>MARX, Matthew Arnold</creator><creator>IVETAC, Anthony</creator><creator>WANG, Xiaolun</creator><scope>EVB</scope></search><sort><creationdate>20231221</creationdate><title>TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS</title><author>LAWSON, John David ; KULYK, Svitlana ; SMITH, Christopher Ronald ; MARX, Matthew Arnold ; IVETAC, Anthony ; WANG, Xiaolun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023244604A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LAWSON, John David</creatorcontrib><creatorcontrib>KULYK, Svitlana</creatorcontrib><creatorcontrib>SMITH, Christopher Ronald</creatorcontrib><creatorcontrib>MARX, Matthew Arnold</creatorcontrib><creatorcontrib>IVETAC, Anthony</creatorcontrib><creatorcontrib>WANG, Xiaolun</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LAWSON, John David</au><au>KULYK, Svitlana</au><au>SMITH, Christopher Ronald</au><au>MARX, Matthew Arnold</au><au>IVETAC, Anthony</au><au>WANG, Xiaolun</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS</title><date>2023-12-21</date><risdate>2023</risdate><abstract>The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
La présente invention concerne des composés qui inhibent au moins une mutation parmi KRas de type sauvage, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D et KRas Q61H, des compositions pharmaceutiques comprenant ces composés et leurs méthodes d'utilisation.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2023244604A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T14%3A27%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LAWSON,%20John%20David&rft.date=2023-12-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2023244604A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |