COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF

The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in pa...

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Bibliographische Detailangaben
Hauptverfasser:	MACOR, John, MUNSON, Mark, GAO, Zhongli, LIAO, Junkai, HURLBUT, Gregory
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis. La présente invention concerne des composés hétérocycliques, des sels pharmaceutiquement acceptables de ceux-ci, et des préparations pharmaceutiques de ceux-ci. L'invention concerne également des compositions et l'utilisation de tels composés dans des méthodes de traitement de maladies et d'affections médiées par une activité CFTR déficiente, en particulier une fibrose kystique.