NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLIC DERIVATIVES AS CHECKPOINT KINASE 1 INHIBITOR AND USES THEREOF
The present disclosure relates generally to nitrogen-containing five-membered heterocyclic derivatives usefulness in treatment of conditions associated with Checkpoint kinase (CHK), particularly more specifically CHK-1 enzymes. Methods of use, compositions, and method of synthesis are also disclosed...
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| creator | CAI, Zhang PANPATIL, Dayanand MA, Jingjing KHAN, Pasha M LIU, Hanlan WANG, Xiaohui YAN, Zhiyu HUANG, Yung-Jen PUJALA, Brahmam RUAN, Juxin |
| description | The present disclosure relates generally to nitrogen-containing five-membered heterocyclic derivatives usefulness in treatment of conditions associated with Checkpoint kinase (CHK), particularly more specifically CHK-1 enzymes. Methods of use, compositions, and method of synthesis are also disclosed.
La présente invention concerne de manière générale des dérivés hétérocycliques à cinq chaînons contenant de l'azote utiles dans le traitement d'états associés à la kinase de point de contrôle (CHK), plus spécifiquement à des enzymes de CHK-1. L'invention concerne également des procédés d'utilisation, des compositions et un procédé de synthèse. |
| format | Patent |
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La présente invention concerne de manière générale des dérivés hétérocycliques à cinq chaînons contenant de l'azote utiles dans le traitement d'états associés à la kinase de point de contrôle (CHK), plus spécifiquement à des enzymes de CHK-1. L'invention concerne également des procédés d'utilisation, des compositions et un procédé de synthèse.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231130&DB=EPODOC&CC=WO&NR=2023226658A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231130&DB=EPODOC&CC=WO&NR=2023226658A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAI, Zhang</creatorcontrib><creatorcontrib>PANPATIL, Dayanand</creatorcontrib><creatorcontrib>MA, Jingjing</creatorcontrib><creatorcontrib>KHAN, Pasha M</creatorcontrib><creatorcontrib>LIU, Hanlan</creatorcontrib><creatorcontrib>WANG, Xiaohui</creatorcontrib><creatorcontrib>YAN, Zhiyu</creatorcontrib><creatorcontrib>HUANG, Yung-Jen</creatorcontrib><creatorcontrib>PUJALA, Brahmam</creatorcontrib><creatorcontrib>RUAN, Juxin</creatorcontrib><title>NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLIC DERIVATIVES AS CHECKPOINT KINASE 1 INHIBITOR AND USES THEREOF</title><description>The present disclosure relates generally to nitrogen-containing five-membered heterocyclic derivatives usefulness in treatment of conditions associated with Checkpoint kinase (CHK), particularly more specifically CHK-1 enzymes. Methods of use, compositions, and method of synthesis are also disclosed.
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLIC DERIVATIVES AS CHECKPOINT KINASE 1 INHIBITOR AND USES THEREOF |
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