COMPOSITIONS AND METHODS FOR TREATING HEPATITIS D VIRUS (HDV) INFECTION AND ASSOCIATED DISEASES

The present disclosure provides methods for treating hepatitis D virus (HDV) infection and/or an HDV-associated disease using combination therapies, and related kits and compositions for use in such methods. The components of the combination therapies may include one or more of an anti-HBV antibody;...

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Hauptverfasser: LAU, Audrey H, GUPTA, Sneha V, CHATTERGOON, Michael A, CLOUTIER, Daniel J, HWANG, Carey K, ELIE, Sophia E
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GUPTA, Sneha V
CHATTERGOON, Michael A
CLOUTIER, Daniel J
HWANG, Carey K
ELIE, Sophia E
description The present disclosure provides methods for treating hepatitis D virus (HDV) infection and/or an HDV-associated disease using combination therapies, and related kits and compositions for use in such methods. The components of the combination therapies may include one or more of an anti-HBV antibody; an siRNA that targets an HBV mRNA; and a nucleos(t)ide reverse transcriptase inhibitor (NRTI). La présente divulgation concerne des méthodes de traitement d'une infection par le virus de l'hépatite D (VHD) et/ou d'une maladie associée au VHD à l'aide de polythérapies, ainsi que des kits et des compositions associés destinés à être utilisés dans de telles méthodes. Les composants des polythérapies peuvent comprendre un ou plusieurs éléments parmi un anticorps anti-VHB ; un pARNi qui cible un ARNm de VHB ; et un inhibiteur de transcriptase inverse (NRTI) à base de nucléosides et de nucléotides.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title COMPOSITIONS AND METHODS FOR TREATING HEPATITIS D VIRUS (HDV) INFECTION AND ASSOCIATED DISEASES
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