ANTIBODY-DRUG CONJUGATE CONTAINING PROTEIN DEGRADATION AGENT BIOACTIVE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF

Provided are an antibody-drug conjugate containing a protein degradation agent bioactive compound represented by formula I, a method for preparing same, and use thereof in preventing and/or treating diseases related to abnormal cell activity, including but not limited to use thereof in preventing an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CAI, Jiaqiang, SONG, Shuai, SHI, Xinzhen, XIAO, Liang, SHAN, Ailin, XUE, Tongtong
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Provided are an antibody-drug conjugate containing a protein degradation agent bioactive compound represented by formula I, a method for preparing same, and use thereof in preventing and/or treating diseases related to abnormal cell activity, including but not limited to use thereof in preventing and/or treating tumor diseases. L'invention concerne un conjugué anticorps-médicament contenant un composé bioactif d'agent de dégradation de protéine représenté par la formule I, son procédé de préparation, et son utilisation dans la prévention et/ou le traitement de maladies associées à une activité cellulaire anormale, comprenant, de façon non limitative, l'utilisation de celui-ci dans la prévention et/ou le traitement de maladies tumorales. 一种式I 所示的蛋白降解剂类生物活性化合物的抗体药物偶联物、其制备方法，以及其在预防和/或治疗与细胞活动异常相关的疾病、包括但不限于在预防和/或治疗肿瘤疾病中的用途。