USES OF AMPHIPHILES IN IMMUNE CELL THERAPY AND COMPOSITIONS THEREFOR

USES OF AMPHIPHILES IN IMMUNE CELL THERAPY AND COMPOSITIONS THEREFOR

The disclosure features amphiphilic ligand conjugates including an EGFR peptide as well as immune cells modified with EGFR receptors. The disclosure also features compositions and methods of using the same, for example, to stimulate proliferation of T cell receptor expressing cells. L'invention...

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Bibliographische Detailangaben
Hauptverfasser: LOGUN, Meghan, BINDER, Zev, DEMUTH, Peter, O'ROURKE, Donald, BABOKHOV, Michael, RODRIGUEZ, Jesse
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:The disclosure features amphiphilic ligand conjugates including an EGFR peptide as well as immune cells modified with EGFR receptors. The disclosure also features compositions and methods of using the same, for example, to stimulate proliferation of T cell receptor expressing cells. L'invention concerne des conjugués de ligands amphiphiles comprenant un peptide EGFR ainsi que des cellules immunitaires modifiées avec des récepteurs d'EGFR. L'invention concerne également des compositions et des procédés d'utilisation de celles-ci, par exemple, pour stimuler la prolifération de cellules exprimant un récepteur de cellules T.