MEANS AND METHODS FOR DETERMINING CELLULAR AVIDITY

The current invention relates to cell-cell interaction and in particular to cellular avidity. Provided are improved means and methods to study cell-cell interaction and characterizing cellular avidity. More in particular, the methods involve studying cell- cell interactions and applying forces in or...

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Bibliographische Detailangaben
Hauptverfasser:	DAVOLI, Serena Alba, DE GROOT, Mattijs, WAWRZYNIECKA, Patrycja Anna, GREGG, Trillian Ashley, DALENBERG, Mirjam Rebekka, VAN LOENHOUT, Marinus Theodorus Johannes
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	The current invention relates to cell-cell interaction and in particular to cellular avidity. Provided are improved means and methods to study cell-cell interaction and characterizing cellular avidity. More in particular, the methods involve studying cell- cell interactions and applying forces in order to break cell-cell bonds in a controllable fashion. Analysing such interactions and breakage of cell bonds in time allows to assess cell-cell binding dynamics. La présente invention concerne l'interaction cellule-cellule et en particulier l'avidité cellulaire. L'invention concerne des moyens et des procédés améliorés pour étudier l'interaction cellule-cellule et caractériser l'avidité cellulaire. Plus particulièrement, les procédés impliquent l'étude d'interactions cellule-cellule et l'application de forces afin de rompre des liaisons cellule-cellule d'une manière contrôlable. L'analyse de telles interactions et la rupture de liaisons cellulaires dans le temps permet d'évaluer la dynamique de liaison cellule-cellule.