COMBINATION OF ALLOSTERIC AND ORTHOSTERIC EGFR INHIBITORS FOR THE TREATMENT OF CANCER

The present invention is directed to the combination therapy of cancer with an allosteric EGFR inhibitor and an orthosteric EGFR inhibitor, as well as uses and pharmaceutical compositions thereof. La présente invention concerne la polythérapie du cancer avec un inhibiteur allostérique de l'EGFR...

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Hauptverfasser: JAESCHKE, Georg, OBST-SANDER, Christa Ulrike, RICCI, Antonio, NAGEL, Yvonne Alice, MARTOGLIO, Bruno
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creator JAESCHKE, Georg
OBST-SANDER, Christa Ulrike
RICCI, Antonio
NAGEL, Yvonne Alice
MARTOGLIO, Bruno
description The present invention is directed to the combination therapy of cancer with an allosteric EGFR inhibitor and an orthosteric EGFR inhibitor, as well as uses and pharmaceutical compositions thereof. La présente invention concerne la polythérapie du cancer avec un inhibiteur allostérique de l'EGFR et un inhibiteur orthopédique de l'EGFR, ainsi que des utilisations et des compositions pharmaceutiques de ceux-ci.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMBINATION OF ALLOSTERIC AND ORTHOSTERIC EGFR INHIBITORS FOR THE TREATMENT OF CANCER
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