COMBINATION OF ALLOSTERIC AND ORTHOSTERIC EGFR INHIBITORS FOR THE TREATMENT OF CANCER

The present invention is directed to the combination therapy of cancer with an allosteric EGFR inhibitor and an orthosteric EGFR inhibitor, as well as uses and pharmaceutical compositions thereof. La présente invention concerne la polythérapie du cancer avec un inhibiteur allostérique de l'EGFR...

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Hauptverfasser:	JAESCHKE, Georg, OBST-SANDER, Christa Ulrike, RICCI, Antonio, NAGEL, Yvonne Alice, MARTOGLIO, Bruno
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to the combination therapy of cancer with an allosteric EGFR inhibitor and an orthosteric EGFR inhibitor, as well as uses and pharmaceutical compositions thereof. La présente invention concerne la polythérapie du cancer avec un inhibiteur allostérique de l'EGFR et un inhibiteur orthopédique de l'EGFR, ainsi que des utilisations et des compositions pharmaceutiques de ceux-ci.