NOVEL BERBERINE ANALOGUE AND USE THEREOF

The present invention relates to a novel berberine analogue CD1-410. It has been identified that the novel berberine analogue promotes the activity of mitophagy, and thus can reduce mitochondria with a damaged structure and/or function. Therefore, the novel berberine analogue according to the presen...

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Bibliographische Detailangaben
Hauptverfasser:	CHO, Jong-hyun, KIM, Young Yeon, CHOI, Semyeong, YUN, Jeanho
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	CHEMISTRY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a novel berberine analogue CD1-410. It has been identified that the novel berberine analogue promotes the activity of mitophagy, and thus can reduce mitochondria with a damaged structure and/or function. Therefore, the novel berberine analogue according to the present invention can be used for preventing, alleviating and/or treating various diseases that can be caused by abnormal mitochondria. La présente invention concerne un nouvel analogue de berbérine CD1-410. Il a été identifié que le nouvel analogue de berbérine favorise l'activité de la mitophagie, et peut ainsi réduire les mitochondries ayant une structure et/ou une fonction endommagées. Par conséquent, le nouvel analogue de berbérine selon la présente invention peut être utilisé pour prévenir, soulager et/ou traiter diverses maladies qui peuvent être provoquées par des mitochondries anormales. 본 발명은 신규 베르베린 유사체인 CD1-410에 관한 것으로서, 상기 신규 베르베린 유사체는 미토파지의 활성을 촉진시키며, 이에 따라 구조 및/또는 기능이 손상된 미토콘드리아를 감소시킬 수 있음이 확인되었다. 따라서, 본 발명에 따른 신규 베르베린 유사체는 비정상 미토콘드리아로 야기될 수 있는 다양한 질환의 예방, 개선, 및/또는 치료 용도로 활용될 수 있다.