PROCESS FOR THE PREPARATION OF R-OXYBUTYNIN HYDROCHLORIDE

The present invention discloses a method for resolving cyclohexylphenyl glycolic acid and the preparation of optically active phenylcyclohexyl glycolate esters. More particularly, the invention provides a process for preparation of optically active R-oxybutynin hydrochloride with high enantiomeric p...

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Bibliographische Detailangaben
Hauptverfasser:	PAGIRE, Ravindra Bhausaheb, PRADHAN, Nitin Sharadchandra, CHAVAN, Ganesh Machhindra, CHOUDHARE, Tukaram Sarjerao, MINHAS, Harpreet Singh, KADAM, Vijay Trimbak, MINHAS, Gurpreet Singh, EDAKI, Dhananjay Uddhavrao
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	The present invention discloses a method for resolving cyclohexylphenyl glycolic acid and the preparation of optically active phenylcyclohexyl glycolate esters. More particularly, the invention provides a process for preparation of optically active R-oxybutynin hydrochloride with high enantiomeric purity of greater than 99%. La présente invention concerne un procédé de résolution d'acide cyclohexylphénylglycolique et la préparation d'esters de phénylcyclohexylglycolate optiquement actifs. Plus particulièrement, l'invention concerne un procédé de préparation de chlorhydrate de R-oxybutynine optiquement actif ayant une pureté énantiomérique élevée supérieure à 99 %.