COMPOSITIONS AND METHODS RELATING TO ENGINEERED RNA POLYMERASES WITH CAPPING ENZYMES

COMPOSITIONS AND METHODS RELATING TO ENGINEERED RNA POLYMERASES WITH CAPPING ENZYMES

Disclosed herein is an engineered fusion enzyme composed of a prokaryotic phage RNA polymerase (T7 RNAP) and a viral capping enzyme (NP868R) for the generation of RNA transcripts containing a 5' 7-methylguanylate cap. Est ici divulguée une enzyme de fusion modifiée composée d'une ARN polym...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KAR, Shaunak, ELLINGTON, Andrew, GARDNER, Elizabeth, GOLLIHAR, Jimmy, SHROFF, Raghav
Format: Patent
Sprache:eng ; fre
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Disclosed herein is an engineered fusion enzyme composed of a prokaryotic phage RNA polymerase (T7 RNAP) and a viral capping enzyme (NP868R) for the generation of RNA transcripts containing a 5' 7-methylguanylate cap. Est ici divulguée une enzyme de fusion modifiée composée d'une ARN polymérase de phages procaryotes (ARNP T7) et d'une enzyme de coiffage virale (NP868R) pour la génération de transcrits d'ARN contenant une coiffe 5'7-méthylguanylate.