ANTIBODY USED TO TREAT CORONAVIRUS INFECTION

The present invention provides an antibody that binds to an extracellular domain of TMPRSS2, said antibody being capable of inhibiting the infection of cells by a betacoronavirus. Also provided are an antigen-binding fragment thereof, and a composition comprising the antibody or the antigen-binding...

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Bibliographische Detailangaben
Hauptverfasser:	MATSUMOTO Takehisa, INOUE Jun-ichiro, KAWAGUCHI Yasushi, IDEI Akiko, ITO Yasushi, ISHIGAKI Hirohito, GOHDA Jin, KITAGAWA Yoshinori, HARADA Michishige, SHIROUZU Mikako, NAKAYAMA Misako, SAITO Takashi, YAMAMOTO Mizuki
Format:	Patent
Sprache:	eng ; fre ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides an antibody that binds to an extracellular domain of TMPRSS2, said antibody being capable of inhibiting the infection of cells by a betacoronavirus. Also provided are an antigen-binding fragment thereof, and a composition comprising the antibody or the antigen-binding fragment. La présente invention concerne un anticorps qui se lie à un domaine extracellulaire de TMPRSS2, ledit anticorps étant capable d'inhiber l'infection de cellules par un bêtacoronavirus. L'invention concerne également un fragment de liaison à l'antigène de celui-ci, et une composition comprenant l'anticorps ou le fragment de liaison à l'antigène. 本発明は、ＴＭＰＲＳＳ２の細胞外ドメインに結合する抗体であって、ベータコロナウイルスの細胞への感染を阻害することができる抗体、またはその抗原結合性断片、および前記抗体またはその抗原結合性断片を含む組成物を提供する。