CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST
Disclosed herein are compounds that are Toll-like receptor (TLR) agonist, conjugates comprising these compounds and cell targeting moiety, pharmaceutical compositions thereof, method of activating toll-like receptors 7 and/or 8 and method for the treatment of diseases or disorders mediated by toll-l...
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creator | CHEN, Lianyong ZHENG, Yong |
description | Disclosed herein are compounds that are Toll-like receptor (TLR) agonist, conjugates comprising these compounds and cell targeting moiety, pharmaceutical compositions thereof, method of activating toll-like receptors 7 and/or 8 and method for the treatment of diseases or disorders mediated by toll-like receptors 7 and/or 8, in particular viral infections and proliferative disorders, such as cancer.
L'invention concerne des composés qui sont un agoniste du récepteur de type Toll (TLR), des conjugués comprenant ces composés et une fraction de ciblage de cellules, des compositions pharmaceutiques associées, un procédé d'activation de récepteurs de type Toll 7 et/ou 8 et un procédé de traitement de maladies ou de troubles médiés par des récepteurs de type Toll 7 et/ou 8, en particulier des infections virales et des troubles prolifératifs, tels que le cancer. |
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L'invention concerne des composés qui sont un agoniste du récepteur de type Toll (TLR), des conjugués comprenant ces composés et une fraction de ciblage de cellules, des compositions pharmaceutiques associées, un procédé d'activation de récepteurs de type Toll 7 et/ou 8 et un procédé de traitement de maladies ou de troubles médiés par des récepteurs de type Toll 7 et/ou 8, en particulier des infections virales et des troubles prolifératifs, tels que le cancer.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231019&DB=EPODOC&CC=WO&NR=2023198195A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231019&DB=EPODOC&CC=WO&NR=2023198195A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN, Lianyong</creatorcontrib><creatorcontrib>ZHENG, Yong</creatorcontrib><title>CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST</title><description>Disclosed herein are compounds that are Toll-like receptor (TLR) agonist, conjugates comprising these compounds and cell targeting moiety, pharmaceutical compositions thereof, method of activating toll-like receptors 7 and/or 8 and method for the treatment of diseases or disorders mediated by toll-like receptors 7 and/or 8, in particular viral infections and proliferative disorders, such as cancer.
L'invention concerne des composés qui sont un agoniste du récepteur de type Toll (TLR), des conjugués comprenant ces composés et une fraction de ciblage de cellules, des compositions pharmaceutiques associées, un procédé d'activation de récepteurs de type Toll 7 et/ou 8 et un procédé de traitement de maladies ou de troubles médiés par des récepteurs de type Toll 7 et/ou 8, en particulier des infections virales et des troubles prolifératifs, tels que le cancer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB39vfzCnV3DHFVcPb3DQjyDPb0c1cI8ffx0fXx9HZVCHJ1dg0I8Q9ScHT39_MMDuFhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGRsaGlhaGlqaOhsbEqQIAu4wnNw</recordid><startdate>20231019</startdate><enddate>20231019</enddate><creator>CHEN, Lianyong</creator><creator>ZHENG, Yong</creator><scope>EVB</scope></search><sort><creationdate>20231019</creationdate><title>CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST</title><author>CHEN, Lianyong ; ZHENG, Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023198195A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN, Lianyong</creatorcontrib><creatorcontrib>ZHENG, Yong</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN, Lianyong</au><au>ZHENG, Yong</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST</title><date>2023-10-19</date><risdate>2023</risdate><abstract>Disclosed herein are compounds that are Toll-like receptor (TLR) agonist, conjugates comprising these compounds and cell targeting moiety, pharmaceutical compositions thereof, method of activating toll-like receptors 7 and/or 8 and method for the treatment of diseases or disorders mediated by toll-like receptors 7 and/or 8, in particular viral infections and proliferative disorders, such as cancer.
L'invention concerne des composés qui sont un agoniste du récepteur de type Toll (TLR), des conjugués comprenant ces composés et une fraction de ciblage de cellules, des compositions pharmaceutiques associées, un procédé d'activation de récepteurs de type Toll 7 et/ou 8 et un procédé de traitement de maladies ou de troubles médiés par des récepteurs de type Toll 7 et/ou 8, en particulier des infections virales et des troubles prolifératifs, tels que le cancer.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST |
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