INJECTABLE HYALURONIC ACID MICROSPHERE, PREPARATION METHOD THEREFOR AND USE THEREOF

An injectable hyaluronic acid microsphere, a preparation method therefor and use thereof. The method comprises: adding cross-linked hyaluronic acid into an aqueous solvent to prepare a first liquid phase, the concentration of the cross-linked hyaluronic acid in the first liquid phase being controlled at 0.1-5 wt%; adding an internal polyester into an organic solvent to prepare a second liquid phase, the concentration of the internal polyester in the second liquid phase being controlled at 0.1-500 mg/mL; and then mixing the first liquid phase with the second liquid phase in a volume ratio of 3-15:1 to prepare the microsphere. Under the same condition, the microsphere is not prone to aggregation and adhesion, and has higher cell adhesion and histocompatibility. Microsphère injectable d'acide hyaluronique, un procédé de préparation associé et une utilisation associée. Le procédé consiste : à ajouter de l'acide hyaluronique réticulé dans un solvant aqueux pour préparer une première phase liquide, la concentration