7-KETOLITHOCHOLIC ACID FOR USE IN THE TREATMENT OF GUT DYSBIOSIS AND AS A PREBIOTIC

7-ketolithocholic acid (7-KCLA, 3α-hydroxy-7-oxo-5β-cholanic acid) and its pharmaceutically acceptable salts and glycine or taurine conjugates are useful for the prevention or treatment of gut dysbiosis, diseases and conditions associated with poor gut health, or in improving the health of the gut m...

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Bibliographische Detailangaben
Hauptverfasser:	WATSON, Kimberley Ann, WEYMOUTH-WILSON, Alexander Charles, GIBSON, Glenn, BASSON, Abigail Rose
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	7-ketolithocholic acid (7-KCLA, 3α-hydroxy-7-oxo-5β-cholanic acid) and its pharmaceutically acceptable salts and glycine or taurine conjugates are useful for the prevention or treatment of gut dysbiosis, diseases and conditions associated with poor gut health, or in improving the health of the gut microbiome. Selon l'invention, l'acide 7-cétolithocholique (acide 7-KCLA, 3α-hydroxy-7-oxo-5β-cholanique) et ses sels pharmaceutiquement acceptables et conjugués de glycine ou de taurine sont utiles pour la prévention ou le traitement de la dysbiose intestinale, de maladies et d'états associés à une mauvaise santé intestinale, ou pour améliorer la santé du microbiome intestinal.