SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES

The present disclosure relates to a process for the regiochemically and enantiomerically controlled synthesis of phosphoramidite-containing monomers, and to intermediate products of this process. In some embodiments, the phosphoramidite-containing monomers or their precursors are regioisomerically a...

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Bibliographische Detailangaben
Hauptverfasser:	KUCHELMEISTER, Hannes, BANASIK, Brent, SIMONYIOVA, Sona, TABONE, John C, PFAFFENEDER, Toni, JACOBS, Aaron, JUD, Lukas, DIAZ CORRAL, Julian Andres, NABAVI, Melud, THUER, Wilma
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS THEIR RELEVANT APPARATUS TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates to a process for the regiochemically and enantiomerically controlled synthesis of phosphoramidite-containing monomers, and to intermediate products of this process. In some embodiments, the phosphoramidite-containing monomers or their precursors are regioisomerically and/or enantiomerically pure and may be polymerized into polymers or copolymers. La présente invention concerne un procédé de synthèse régiochimiquement et énantiomériquement contrôlée de monomères contenant des phosphoramidites, et des produits intermédiaires de ce procédé. Dans certains modes de réalisation, les monomères contenant des phosphoramidites ou leurs précurseurs sont régioisomériquement et/ou énantiomériquement purs et peuvent être polymérisés en polymères ou copolymères.