SPLEEN TYROSINE KINASE INHIBITOR, COMPOSITION, AND METHODS OF USE
Compounds, compositions and methods for inhibiting Syk from phosphorylating erythrocyte anion transporter band 3 and/or Syk tyrosine kinase. Further disclosed are methods of treating a subject for a disease involving the release of microvesicles from blood cells, including alpha-thalassemia or beta-...
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| creator | HAUSMAN, John SRINIVASARAO, Madduri LOW, Philip YARLAGADDA, Suresh |
| description | Compounds, compositions and methods for inhibiting Syk from phosphorylating erythrocyte anion transporter band 3 and/or Syk tyrosine kinase. Further disclosed are methods of treating a subject for a disease involving the release of microvesicles from blood cells, including alpha-thalassemia or beta-thalassemia, sickle cell disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency or glutathione reductase deficiency.
L'invention concerne des composés, des compositions et des procédés permettant d'empêcher la Syk de phosphoryler la bande transporteuse d'anions érythrocytaires 3 et/ou la tyrosine kinase Syk. |
| format | Patent |
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L'invention concerne des composés, des compositions et des procédés permettant d'empêcher la Syk de phosphoryler la bande transporteuse d'anions érythrocytaires 3 et/ou la tyrosine kinase Syk.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SPLEEN TYROSINE KINASE INHIBITOR, COMPOSITION, AND METHODS OF USE |
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