NOVEL 2-(PHENYLAMINO)PYRIDINE-BASED TEAD INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel 2-(phenylamino)pyridine derivative and a pharmaceutical composition comprising same as an active ingredient for prevention or treatment of cancer, and the compound represented by chemical formula 1 described in the present specification exhibits excellent inh...

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Bibliographische Detailangaben
Hauptverfasser:	KANG, Seok-Gu, KIM, Yoon-Jung, OH, Yoojung, CHOI, Ran Joo, CHOI, Yong-Sung, JEON, Raok
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a novel 2-(phenylamino)pyridine derivative and a pharmaceutical composition comprising same as an active ingredient for prevention or treatment of cancer, and the compound represented by chemical formula 1 described in the present specification exhibits excellent inhibitory activity on TEAD and thus is expected to be useful for the prevention or treatment of cancer. La présente invention concerne un nouveau dérivé de 2-(phénylamino)pyridine et une composition pharmaceutique le comprenant en tant que principe actif pour la prévention ou le traitement du cancer, et le composé représenté par la formule chimique 1 décrit dans la présente invention a une excellente activité inhibitrice sur TEAD et est ainsi censé être utile pour la prévention ou le traitement du cancer. 본 발명은 신규한 2-(페닐아미노)피리딘 유도체, 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 명세서에 기재된 화학식 1로 표시되는 화합물은 TEAD에 대한 우수한 억제 활성을 나타내면서, 암의 예방 또는 치료에 유용할 것으로 기대된다.