A METHOD FOR DIAGNOSIS OF TRAUMATIC BRAIN INJURY

The present disclosure relates to in vitro methods for diagnosing traumatic brain injury (TBI), in particular to methods wherein the diagnosis is based on determining level of glycan-based biomarkers in saliva and/or urine of a subject suspected to suffer from TBI. The disclosure also relates to use...

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Bibliographische Detailangaben
Hauptverfasser:	VÄLIMAA, Lasse, HAREL, Adrian, HAAVISTO, Oskar, KVIST, Mårten
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present disclosure relates to in vitro methods for diagnosing traumatic brain injury (TBI), in particular to methods wherein the diagnosis is based on determining level of glycan-based biomarkers in saliva and/or urine of a subject suspected to suffer from TBI. The disclosure also relates to use of specific N-glycans as biomarkers of TBI in saliva and urine. La présente divulgation concerne des méthodes in vitro pour diagnostiquer un traumatisme crânio-cérébral (TBI), en particulier des méthodes dans lesquelles le diagnostic est basé sur la détermination du niveau de biomarqueurs à base de glycane dans la salive et/ou l'urine d'un sujet suspecté de souffrir de TBI. La divulgation concerne également l'utilisation de N-glycanes spécifiques en tant que biomarqueurs de TBI dans la salive et l'urine.