RE-SENSITIZING MULTIDRUG-RESISTANT (MDR) GRAM-NEGATIVE BACTERIA TO COLISTIN USING IONOPHORES

The present invention is directed to novel resistance modifying agents (RMAs) compounds configured to potentiate antibiotic compounds, such as polymyxin antibiotics, including colistin, directed to multi-drug resistance (MDR) gram-negative bacteria. La présente invention concerne de nouveaux composé...

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Bibliographische Detailangaben
Hauptverfasser:	GAO, Yuefeng, DUTTA, Somnath, LIU, Nianzi, WANG, Xiang
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention is directed to novel resistance modifying agents (RMAs) compounds configured to potentiate antibiotic compounds, such as polymyxin antibiotics, including colistin, directed to multi-drug resistance (MDR) gram-negative bacteria. La présente invention concerne de nouveaux composés modificateurs de résistance (RMAs) conçus pour potentialiser des composés antibiotiques, tels que des antibiotiques de polymyxine, comprenant de la colistine, dirigés contre des bactéries à Gram négatif à résistance multiple aux médicaments (MDR).